ProxAI

Your target interface picks the modality.

Target-first.
Four modulator modalities, chosen strictly on the merits of your target's binding interface.

Repertoire of Modulator Modalities
Antibody Fragments
Modality 01

Antibody

Fab / scFv designs with established manufacturing and regulatory precedent.

Best For: Extracellular targets and therapeutic translation.
Use Cases:
IND-enabling biologic Therapeutic translation Diagnostics & Lab Reagents
Nanobodies
Modality 02

Nanobody

Single-domain VHH framework with camelid-derived loop flexibility.

Best For: Concave epitopes, cryptic pockets, intrabody applications.
Use Cases:
Cryptic epitope PPI disruptor bioPROTAC mRNA-ENCODED
Minibinders
Modality 03

Minibinders

De novo scaffolds offering high stability and precise interface targeting.

Best For: Compact and hydrophobic interfaces. Highly stable.
Use Cases:
PPI disruptor Intracellular bioPROTAC mRNA-ENCODED
Cyclic Peptides
Modality 04

Cyclic Peptides

Constrained macrocycles with cell permeability and oral bioavailability potential.

Best For: Flat PPI interfaces and shallow groove binding. Cell penetration.
Use Cases:
Ortho & Allosteric ligand Payload vector (PDC)